What is one effect NOT caused by carbonic anhydrase inhibitors?

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Carbonic anhydrase inhibitors are medications that primarily work by inhibiting the enzyme carbonic anhydrase, which plays a crucial role in the regulation of acid-base balance in the body and in the reabsorption of bicarbonate in the kidneys. By blocking this enzyme, these inhibitors can lead to various physiological effects and side effects.

One significant effect not caused by carbonic anhydrase inhibitors is the change in the color of the iris. Changes in iris color are typically related to other factors, such as genetics, certain medications that affect pigmentation, or specific conditions affecting the eye. Carbonic anhydrase inhibitors do not have a known pharmacological effect on the pigmentation of the iris or any mechanism that would lead to a change in iris color.

In contrast, numbness and tingling of the hands and feet, known as peripheral neuropathy, can occur due to alterations in electrolyte balance, particularly with decreased bicarbonate levels, which can affect nerve function. Kidney stones can also result as a consequence of the metabolic changes induced by these inhibitors, which may alter urinary pH and promote stone formation. Drowsiness and fatigue are common side effects associated with many medications, including carbonic anhydrase inhibitors, due to their impact on fluid balance and

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